Safety and Tolerability of BAY1862864 Injection in Subjects With Relapsed or Refractory CD22-positive Non-Hodgkin's Lymphoma

PHASE1CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

November 20, 2015

Primary Completion Date

November 11, 2019

Study Completion Date

November 26, 2019

Conditions
Lymphoma, Non-Hodgkin
Interventions
DRUG

BAY1862864

Radiopharmaceutical, injection: Up to four treatment cycles lasting six weeks each; in each cycle, a single treatment on Day 1. In this dose-escalation part of the study, the radioactivity dose will start at 1.5 MBq and increase in steps of 1.5 MBq, with a antibody-chelator conjugate dose of 2 or 10 mg.

Trial Locations (4)

221 85

Skanes Universitetssjukhus, Lund

SO16 6YD

Southampton General Hospital, Southampton

SM2 5PT

Royal Marsden NHS Trust (Surrey), Sutton

NW3 2QG

Royal Free Hospital, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY