Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition

NACompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

November 30, 2017

Study Completion Date

November 30, 2017

Conditions
Barrett's EsophagusGastroesophageal Reflux Disease
Interventions
OTHER

Cessation of Acid Suppressing Medications

Acid suppressing medications are stopped for all participants the day after baseline assessment. Subsequent evaluations are performed while the participant is not on acid-suppressing medications. Endoscopy with biopsies will be performed in all patients on day 0, 7, and 14.

Trial Locations (1)

75216

Dallas VA Medical Center, Dallas

Sponsors
All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Dallas VA Medical Center

FED