Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery

PHASE2CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

February 28, 2014

Study Completion Date

February 28, 2014

Conditions
Progressive Infantile Idiopathic Scoliosis
Interventions
DRUG

Ketamine Hydrochloride

50 mg/ml, IV (in the vein) during surgery operation, followed by IV ketamine hydrocloride perfusion 2mcg/Kg/min before and until 72 hours after operation Number of Cycles: until progression or unacceptable toxicity develops.

OTHER

Placebo

50 mg/ml, IV (in the vein) during surgery operation, followed by IV placebo perfusion 2mcg/Kg/min before and until 72 hours after operation

DRUG

Remifentanil

at doses of 0.3 mcg / kg / min during and until the end of the surgical operation

DRUG

Morphine hydrochloride

at the dose of 150 mcg / kg, 60 minutes before the extubation procedure and until 72 hours after operation by intravenous infusion

Trial Locations (1)

08950

Hospital Sant Joan de Déu, Esplugues de Llobregat

All Listed Sponsors
collaborator

Instituto de Salud Carlos III

OTHER_GOV

lead

Fundació Sant Joan de Déu

OTHER

NCT02571491 - Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery | Biotech Hunter | Biotech Hunter