Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore

PHASE1/PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

December 31, 2018

Primary Completion Date

August 8, 2019

Study Completion Date

August 8, 2019

Conditions
Dengue Fever
Interventions
DRUG

Celgosivir

Celgosivir 150 mg Q6H for 5 days (total of 20 doses = 3000 mg celgosivir total).

DRUG

Modipafant 50mg

Modipafant 50 mg Q12H alternating with placebo Q12H for 5 days (total of 10 modipafant doses = 500 mg modipafant)

DRUG

Placebo

Placebo Q6H for 5 days

DRUG

Modipafant 100mg

Modipafant 100 mg Q12H alternating with placebo Q12H for 5 days (total of modipafant 10 doses = 1000 mg modipafant)

Trial Locations (1)

169608

Singhealth Investigational Medicine Unit, Singapore

Sponsors
All Listed Sponsors
collaborator

Duke-NUS Graduate Medical School

OTHER

collaborator

60 Degrees Pharmaceuticals LLC

INDUSTRY

lead

Singapore General Hospital

OTHER

NCT02569827 - Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore | Biotech Hunter | Biotech Hunter