Oral Mucositis and Laser Therapy Associated With Photodynamic Therapy

PHASE3CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2015

Conditions
Oral Mucositis
Interventions
OTHER

PDT + Low level laser

"Two days before the laser treatment, the side of the oral cavity chosen for the experimental treatment was pigmented with aqueous solution of 0.005% methylene blue. A ball of sterile cotton was soaked in the dye solution and placed in the center of the lesion. Photosensitizer remained in the place for 5 minutes (pre-irradiation period). Then, to activate the dye, the lesion was irradiated with red light (InGaAlP / phosphide and Indium, Gallium and potassium).~From the 3rd to the 10th day was carried out only laser therapy. For laser therapy was first used infrared emitter laser unit with active medium AsGaAl (Gallium Arsenide and Aluminium). Then, we used the red emitter, whose active medium was the InGaAlP (phosphide and Indium, Gallium and Potassium)."

RADIATION

Low level laser

Two days before the laser treatment, the lesion of the side of the oral cavity chosen for the control treatment was treated with ball of sterile cotton soaked in distilled water and the laser unit placed on the lesion without activation of the light. From the 3rd to the 10th day was carried out laser therapy. For laser therapy was first used infrared emitter laser unit with active medium AsGaAl (Gallium Arsenide and Aluminium). Then, we used the red emitter, whose active medium was the InGaAlP (phosphide and Indium, Gallium and Potassium).

Trial Locations (1)

65031-630

Hospital Aldenora Bello, São Luís

All Listed Sponsors
collaborator

Fundação de Amparo à Pesquisa e Desenvolvimento Científico do Maranhão

UNKNOWN

lead

Universidade Ceuma

OTHER

NCT02555501 - Oral Mucositis and Laser Therapy Associated With Photodynamic Therapy | Biotech Hunter | Biotech Hunter