NCT02551614View on ClinicalTrials.gov

Neutrophil Imaging in Healthy Subjects Following Lipopolysaccharide or Saline Challenge and in Subjects With Chronic Obstructive Pulmonary Disease

PHASE1CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

March 17, 2015

Primary Completion Date

May 24, 2016

Study Completion Date

May 24, 2016

Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
PROCEDURE

Lipopolysaccharide challenge

Lipopolysaccharide solution inhaled using a dosimeter.

PROCEDURE

Saline challenge

0.9% sodium chloride solution inhaled using dosimeter.

PROCEDURE

Labelled neutrophils and Imaging assessment

Injection of labelled neutrophils and imaging assessments

Trial Locations (2)

CB2 0QQ

GSK Investigational Site, Cambridge

CB2 2GG

GSK Investigational Site, Cambridge

Sponsors

Lead Sponsor

GlaxoSmithKline
All Listed Sponsors
collaborator

University of Cambridge

OTHER

lead

GlaxoSmithKline

INDUSTRY

NCT02551614 - Neutrophil Imaging in Healthy Subjects Following Lipopolysaccharide or Saline Challenge and in Subjects With Chronic Obstructive Pulmonary Disease | Biotech Hunter | Biotech Hunter