A Phase I/II Study of Gene-modified WT1 TCR Therapy in MDS & AML Patients

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

September 30, 2015

Primary Completion Date

May 31, 2018

Study Completion Date

May 31, 2018

Conditions
Myelodysplastic Syndromes (MDS)Acute Myeloid Leukaemia (AML)
Interventions
GENETIC

Autologous WT1 TCR transduced T cells

Gene therapy: Autologous WT1 TCR transduced T cells administered by intravenous infusion

Trial Locations (6)

B-8000

AZ St Jan Brugge-Oostende AV, Bruges

B - 3000

UZ Leuven, Leuven

01307

Uniklinikum Dresden, Dresden

BS2 8ED

University Hospitals Bristol NHS Foundation Trust, Bristol

LS2 9LN

The Leeds Teaching Hospitals NHS Trust, Leeds

NW1 2PG

University College London Hospitals NHS Trust, London

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

University College, London

OTHER

collaborator

Cell Therapy Catapult

OTHER

lead

Cell Medica Ltd

INDUSTRY

NCT02550535 - A Phase I/II Study of Gene-modified WT1 TCR Therapy in MDS & AML Patients | Biotech Hunter | Biotech Hunter