7,830
Participants
Start Date
December 14, 2015
Primary Completion Date
October 31, 2018
Study Completion Date
October 31, 2018
DMPA
Women randomized to DMPA, will receive an intramuscular injection of DMPA (medroxyprogesterone acetate sterile aqueous suspension 150 mg per 1 mL) at enrolment. Subsequent injections will be given every 3 months (i.e., at quarterly study visits) at the study site.
LNG
Women randomized to implants will receive LNG implants in the arm, at enrolment from trained clinicians.
Copper IUD
Women randomized to IUDs will receive their IUDs at enrolment. Trained providers will insert T380a copper IUDs using standard insertion techniques.
Aurum Klerksdorp Gavin Churchyard Legacy Centre, Klerksdorp
Effective Care Research Unit (ECRU) Frere Maternity Hospital, East London
FLAS/ICAP Clinic 1& Clinic 2, Manzini
Kisumu East Research Care and Training Program, Kisumu
Madibeng Centre for Research, Brits
Emavundleni Research Centre, Cape Town
MatCH Research Unit Commercial City, Durban
Wits Reproductive Health and HIV Institute (WRHI), Johannesburg
QM ladysmith, Ladysmith
MatCH Research Unit Edendale, Pietermaritzburg
Setshaba Research Centre, Soshanguve
University Teaching Hospital, Lusaka, Zambia, Lusaka
Collaborators (2)
University of Washington
OTHER
Wits Reproductive Health and HIV Institute
OTHER
World Health Organization
OTHER
Madibeng Centre for Research
OTHER
Maternal Adolescent and Child Health Research
UNKNOWN
Qhakaza Mbokodo Research Clinic
UNKNOWN
The Aurum Institute NPC
OTHER
Effective Care Research Unit
OTHER
Emavundleni Research Centre
UNKNOWN
Setshaba Research Centre
UNKNOWN
University of North Carolina, Chapel Hill
OTHER
Family Life Association of Swaziland
UNKNOWN
ICAP Columbia University
UNKNOWN
Kenya Medical Research Institute
OTHER
FHI 360
OTHER