NCT02545452 - Effect of Concomitant Use of an Antimycotic, an Antibiotic, a Spermicide or Tampons on Pharmacokinetics of Anastrozole and Levonorgestrel Released From Intra-vaginal Ring | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 15, 2015

Primary Completion Date

March 14, 2016

Study Completion Date

July 29, 2016

Conditions

Endometriosis

Interventions

DRUG

Anastrozole / Levonorgestrel (BAY98-7196)

Release rate of the IVR: 1050 μg/d ATZ + 40 μg/d LNG

DRUG

Gyno-Daktarin

400 mg miconazole nitrate per day for 3 consecutive days

DRUG

Sobelin vaginal creme

100 mg clindamycin 2-dihydrogen phosphat per day for 3 consecutive days

DRUG

Patentex oval

75 mg Nonoxynol-9 per day for 3 consecutive days

OTHER

Tampon

Trial Locations (1)

Berlin