Effectiveness of KAE609 in Reducing Asexual & Sexual Blood-stage P.Falciparum Infection & Infectivity to Mosquitos

PHASE1TerminatedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2015

Conditions
Plasmodium Falciparum Malaria
Interventions
DRUG

KAE609

Study drug

DRUG

Piperaquine Phosphate

Pre-administration of Piperaquine Phosphate will be done to eliminate the asexual form of the parasite and induce gametocytaemia before characterizing the activity of KAE609 in clearing sexual blood stage parasites from the blood of healthy subjects in the Induced Blood Stage Malaria Challenge model in Part B of study

Trial Locations (1)

4006

Novartis Investigative Site, Brisbane

Sponsors
All Listed Sponsors
collaborator

Medicine for Malaria Venture

UNKNOWN

lead

Novartis Pharmaceuticals

INDUSTRY