A Study of Lenalidomide in Pediatric Subjects With Relapsed or Refractory Acute Myeloid Leukemia

PHASE2CompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

November 19, 2015

Primary Completion Date

July 22, 2017

Study Completion Date

January 11, 2019

Conditions
Leukemia, Myeloid
Interventions
DRUG

Lenalidomide

Lenalidomide will be administered orally once daily for the first 21 days of every 28-day cycle. The starting dose will be 2 mg/kg/day with a maximum dose of 70 mg/day. Number of cycles: 12, or until evidence of progressive disease. Participants will also be discontinued if unresolved toxicities as described in the protocol occur, or if dose reductions are required and subject does not tolerate minimum dose level of 1mg/kg/day.

Trial Locations (62)

10032

Columbia University Medical Center, New York

10595

New York Medical College, Valhalla

14263

Roswell Park Cancer Inst, Buffalo

14642

University of Rochester Medical Center, Rochester

15224

UPMC Childrens Hospital of Pittsburgh, Pittsburgh

17033

Penn State Milton S Hershey Medical Center, Hershey

19803

Alfred I Dupont Hospital For Children, Wilmington

21287

Johns Hopkins University, Baltimore

23507

Children's Hospital of The King's Daughters, Norfolk

27599

University of North Carolina, Chapel Hill

28203

Carolinas Healthcare System, Charleston

29605

Greenville Health System, Greenville

30322

Children's Healthcare of Atlanta, Atlanta

32207

Nemours Children's Clinic, Jacksonville

33701

All Children's Hospital, St. Petersburg

33908

Golisano Children's Hospital of Southwest Florida, Fort Myers

35294

Children's Hospital, Birmingham

37212

Vanderbilt University Medical Center, Nashville

39216

University of Mississippi Medical Center, Jackson

40202

Kosair Children's Hospital, Louisville

43205

Nationwide Children's Hospital, Columbus

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

46202

Riley Hospital For Children at IU Health, Indianapolis

48109

University of Michigan, Ann Arbor

53226

Midwest Children's Cancer Center, Milwaukee

55404

Children's Hospitals and Clinics of Minnesota, Minneapolis

55455

University of Minnesota, Minneapolis

60453

Advocate Chilldren's Hospital, Oak Lawn

60611

Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago

63110

Washington University School of Medicine, St Louis

64108

Children's Mercy Hospital, Kansas City

70118

Children's Hospital New Orleans, New Orleans

72202

Arkansas Children's Hospital, Little Rock

75235

University of Texas Southwestern Medical Center, Dallas

77030

Texas Children's Cancer Center, Houston

78229

Methodist Hospital, San Antonio

78723

Dell Children's Medical Center of Central Texas, Austin

80045

Colorado Children's Hospital, Aurora

84113

Primary Children's Medical Center, Salt Lake City

85016

Phoenix Childrens Hospital, Phoenix

89109

Children's Specialty Center of Nevada, Las Vegas

90027

Children's Hospital of Los Angeles, Los Angeles

Southern California Permanente Medical Group, Los Angeles

90806

Miller Children's Hospital, Long Beach

92408

Loma Linda University, San Bernardino

92868

Children's Hospital of Orange County, Orange

93636

Valley Children's Hospital, Madera

94143

UCSF Children's Hospital, San Francisco

94304

Lucile Salter Packard Children's Hospital at Stanford, Palo Alto

97227

Legacy Emanuel Hospital and Health Center, Portland

98105

Seattle Children's Hospital, Seattle

06106

Connecticut Children's Medical Center, Hartford

20010-2970

Children's Hospital National Medical Center, Washington D.C.

07601

Hackensack University Medical Center, Hackensack

07962

Morristown Memorial Hosp, Morristown

08903

Cancer Institute of New Jersey, New Brunswick

T3B 6A8

Alberta Childrens Hospital, Calgary

V6H3V4

British Columbia Children's Hospital, Vancouver

B3K 6R8

IWK Health Center, Halifax

K1H 8L1

Childrens Hospital of Eastern Ontario, Ottawa

H4A 3J1

McGill University Health Center, Montreal

M5G 1X8

Hospital For Sick Children, Torento

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY