NCT02532998 - A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 30, 2015

Primary Completion Date

December 31, 2015

Study Completion Date

December 31, 2015

Conditions

PharmacodynamicsHealthy Subjects

Interventions

DRUG

AZD9977 oral suspension

AZD9977 oral suspension, single dose

DRUG

AZD9977 placebo oral suspension

oral suspension, single dose

DRUG

Fludrocortisone, tablets

Loading dose of 0.5 mg and maintenance doses of 0.1 mg every second hour up to a total dose of 1.0 mg per treatment period (may be modified to up to 1.3 mg based on emerging data)

DRUG

Eplerenone, tablets

100 mg (2 x 50 mg tablets) single dose, may be modified based on emerging data (will not exceed 500 mg per treatment period)

Trial Locations (1)

Unknown

Research Site, Harrow