The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil

PHASE2Active, not recruitingINTERVENTIONAL

Enrollment

160

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

August 31, 2025

Study Completion Date

August 31, 2026

Conditions

Leishmaniasis

Interventions

DRUG

Meglumine antimoniate

20mgSb+5/kg/day meglumine antimoniate intravenous for 28 days.

DRUG

Miltefosine

Miltefosine 2,5mg/kg/day up to 50mg 2x/daily.

DRUG

Pentoxifylline

Pentoxifylline 20mg/kg/day up to 400mg 3x/daily for 28 days.

Trial Locations (1)

Hospital Universitário de Brasília, Brasília

All Listed Sponsors

lead

University of Brasilia

OTHER