59
Participants
Start Date
November 4, 2015
Primary Completion Date
October 31, 2022
Study Completion Date
October 31, 2022
Lenalidomide
"Phase I Starting Dose Level: 15 mg by mouth on Days 1 - 14 of each 21 day cycle.~Phase II Starting Dose Level: Maximum tolerated dose from Phase I."
Obinutuzumab
Phase I and II: 1000 mg by vein on Days 1, 8, and 15 of Cycle 1 and Day 1 of Cycles 2 - 6.
Cyclophosphamide
Phase I and II: 750 mg/m2 vein over about 1 hour on Day 1 of all cycles.
Doxorubicin
Phase I and II: 50 mg/m2 by vein over about 15 minutes each on Day 1 of all cycles.
Vincristine
Phase I and II: 1.4 mg/m2 by vein on Day 1 of all cycles.
Prednisone
Phase I and II: 100 mg by mouth daily on Days 1 - 5 of each 21 day cycle.
University of Texas MD Anderson Cancer Center, Houston
Collaborators (2)
Celgene
INDUSTRY
Genentech, Inc.
INDUSTRY
M.D. Anderson Cancer Center
OTHER