Effect of Inhibitors of the Proton Pump on Intestinal Transporters

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

May 31, 2015

Study Completion Date

December 31, 2015

Conditions
Healthy
Interventions
DRUG

Dabigatran

dabigatran etexilate 150 mg/day (1 day)

DRUG

Rabeprazole and Dabigatran

rabeprazole 20 mg / day for 5 days, then the 6th day concomitant rabeprazole 20 mg of dabigatran etexilate 150 mg;

DRUG

Omeprazole and Dabigatran

omeprazole 20 mg / day for 5 days, then the sixth day concomitant omeprazole 20 mg and 150 mg dabigatran etexilate

Trial Locations (1)

42000

CHU de SAINT-ETIENNE, Saint-Etienne

All Listed Sponsors
lead

Centre Hospitalier Universitaire de Saint Etienne

OTHER

NCT02524210 - Effect of Inhibitors of the Proton Pump on Intestinal Transporters | Biotech Hunter | Biotech Hunter