Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degeneration

PHASE2CompletedINTERVENTIONAL
Enrollment

225

Participants

Timeline

Start Date

September 28, 2015

Primary Completion Date

April 10, 2018

Study Completion Date

March 28, 2019

Conditions
Macular Degeneration
Interventions
DRUG

Ranibizumab

Ranibizumab will be administered at dose of 0.5 mg monthly ITV injections of 10-mg/mL formulation or delivered through the implant with three different formulations.

Trial Locations (50)

14620

Retina Assoc of Western NY, Rochester

20815

Retina Group of Washington, Chevy Chase

21204

Retina Specialists, Towson

21287

Johns Hopkins Med; Wilmer Eye Inst, Baltimore

23502

Wagner Macula & Retina Center, Norfolk

28210

Char Eye Ear &Throat Assoc, Charlotte

29501

Palmetto Retina Center, Florence

30909

Southeast Retina Center, Augusta

32503

Retina Specialty Institute, Pensacola

33426

Florida Eye Microsurgical Inst, Boynton Beach

33609

Retina Associates of Florida, LLC, Tampa

33711

Retina Vitreous Assoc of FL, St. Petersburg

33912

National Ophthalmic Research Institute, Fort Myers

37203

Tennessee Retina PC., Nashville

38138

Charles Retina Institute, Germantown

40509

Retina Associates of Kentucky, Lexington

42001

Paducah Retinal Center, Paducah

44195

The Cleveland Clinic Foundation, Cleveland

45242

Cincinnati Eye Institute, Cincinnati

49546

Foundation for Vision Research, Grand Rapids

50266

Wolfe Eye Clinic, West Des Moines

55435

Vitreoretinal Surgery, Edina

60435

Illinois Retina Associates, Joliet

76012

Texas Retina Associates, Arlington

77401

Retina Consultants of Texas, Bellaire

78240

Med Center Ophthalmology Assoc, San Antonio

78750

Retina Research Center, Austin

80228

Colorado Retina Associates, PC, Lakewood

80909

Retina Consultants of Southern, Colorado Springs

84107

Retina Associates of Utah, Salt Lake City

85014

Retinal Research Institute, LLC, Phoenix

85020

Associated Retina Consultants, Phoenix

85206

Barnet Dulaney Perkins Eye Center, Mesa

87102

Eye Associates of New Mexico, Albuquerque

87131

University of New Mexico; School of Med, Albuquerque

89502

Sierra Eye Associates, Reno

91436

The Retina Partners, Encino

92037

Jacobs Retina center at the Shiley eye Institute UCSD, La Jolla

92705

Orange County Retina Med Group, Santa Ana

93103

California Retina Consultants, Santa Barbara

94040

N CA Retina Vitreous Assoc, Mountain View

94109

West Coast Retina Medical Group, San Francisco

94143

UCSF; Ophthalmology, San Francisco

95825

Retinal Consultants Med Group, Sacramento

97221

Retina Northwest, Portland

97239

Oregon HSU; Casey Eye Institute, Portland

90095-7000

Jules Stein Eye Institute/ UCLA, Los Angeles

01605

Vitreo-Retinal Associates, PC, Worcester

07003

Retina Center of New Jersey, Bloomfield

08034

Mid Atlantic Retina - Wills Eye Hospital, Cherry Hill

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY