Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones

PHASE2CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

August 31, 2016

Study Completion Date

January 31, 2017

Conditions
Secondary HyperoxaluriaNephrolithiasisKidney StonesHyperoxaluriaDietary Hyperoxaluria
Interventions
DRUG

ALLN-177 low dose

ALLN-177 1,500 units (1 capsule)/meal PO 3 times per day

DRUG

ALLN-177 mid dose

ALLN-177 3,000 units (2 capsules)/meal PO 3 times per day

DRUG

ALLN-177 high dose

ALLN-177 7,500 units (5 capsules)/meal PO 3 times per day

DRUG

Placebo

Placebo: 1, 2 or 5 capsules with meals PO 3 times per day

Trial Locations (16)

10016

New York University - Division Of Nephrology, New York

11042

North Shore Long Island Jewish Health System/The Arthur Miller Institute for Urology, Lake Success

11694

Brooklyn Urology Research Group, Brooklyn

21401

Anne Arundel Urology, Annapolis

23462

Urology of Virginia, Virginia Beach

32114

Atlantic Urological Associates, Daytona Beach

32224

Mayo Clinic - Nephrology And Hypertension, Jacksonville

44195

Cleveland Clinic-Urology, Cleveland

45212

The Urology Group, Cincinnati

46202

IU Health Physicians Urology, Indianapolis

55902

Mayo Clinic, Rochester

60611

Northwestern Feinberg School Of Medicine - Urology Department, Chicago

75390

UT Southwestern Medical Center - Urology, Dallas

90048

Tower Urology, Los Angeles

02114

Massachusetts General Hospital, Boston

02886

Omega Clinical Research, Warwick

Sponsors
All Listed Sponsors
lead

Allena Pharmaceuticals

INDUSTRY

NCT02503345 - Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones | Biotech Hunter | Biotech Hunter