Degradation of the Anorexic Hormone Peptide YY

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

May 31, 2014

Primary Completion Date

July 31, 2015

Study Completion Date

July 31, 2015

Conditions
Healthy
Interventions
BIOLOGICAL

PYY1-36 infusion

Infusion of 1.6 pmol/kg/min PYY1-36 for 2 hrs.

BIOLOGICAL

PYY1-36 + sitagliptin

Infusion of 1.6 pmol/kg/min PYY1-36 for 2 hrs. Two doses of 100 mg sitagliptin are administered 10 and 1 hour before start of infusion, respectively.

BIOLOGICAL

PYY3-36 infusion

0.8 pmol/kg/min infusion of PYY3-36.

BIOLOGICAL

placebo

Infusion of saline for 2 hrs.

Trial Locations (1)

DK-2650

Department of Endocrinology, Hvidovre Hospital, Hvidovre

All Listed Sponsors
collaborator

University of Copenhagen

OTHER

lead

Hvidovre University Hospital

OTHER

NCT02493959 - Degradation of the Anorexic Hormone Peptide YY | Biotech Hunter | Biotech Hunter