Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

July 31, 2018

Primary Completion Date

January 31, 2020

Study Completion Date

January 31, 2022

Conditions
Nicotine Dependence
Interventions
DRUG

Nicotine patch

21 mg/24 h for 2 weeks before the quit date and 12 weeks after the quit date, 14 mg/24 h for 2 weeks, and 7 mg/ 24 h for 2 weeks.

OTHER

ENDS

As needed for 1 week before the quit date and 8 weeks after the quit date, then reduced use for 4 weeks.

OTHER

Placebo patch

21 mg size for 2 weeks before the quit date and 12 weeks after the quit date, 14 mg size for 2 weeks, and 7 mg size for 2 weeks.

OTHER

Placebo ENDS

As needed for 1 week before the quit date and 8 weeks after the quit date, then reduced use for 4 weeks.

Trial Locations (1)

27705

Duke Center for Smoking Cessation, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Duke University

OTHER