NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

231

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

February 28, 2015

Study Completion Date

February 28, 2015

Conditions
Radiographic Contrast Agent NephropathyPulmonary Embolism
Interventions
DRUG

NAC

3 gr NAC was made up to 1000 ml with NS; a 1 ml/3 mgr NAC solution was obtained and 3 ml/kg NAC+NS solution was administered for 1 h before CTPA and a 1 ml/kg per hour NAC+NS solution was administered for a minimum 6 h after CTPA.

DRUG

NaHCO3

132 mEq NaHCO3 was made up to 1000 ml with NS; and 3 ml/kg NaHCO3+NS solution was administered for 1 h before CTPA and 1 ml/kg per hour NaHCO3+NS solution was administered for a minimum of 6 h after CTPA.

DRUG

Normal Saline

3 ml/kg NS was administered for 1 h before CTPA and 1 ml/kg per hour was administered for a minimum of 6 h after CTPA.

Trial Locations (1)

61080

Karadeniz Technical University Faculty of Medicine, Trabzon

All Listed Sponsors
lead

Karadeniz Technical University

OTHER

NCT02483143 - NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial | Biotech Hunter | Biotech Hunter