Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism

PHASE4CompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

September 22, 2014

Primary Completion Date

March 11, 2015

Study Completion Date

March 11, 2015

Conditions
Postoperative Nausea and Vomiting
Interventions
DRUG

Ramosetron

ramosetron 0.3 mg IV 20 min before the end of surgery and 24 h after the surgery

DRUG

Palonosetron

palonosetron 0.075 mg IV 20 min before the end of surgery and 24 h after the surgery.

Trial Locations (1)

120-752

Department of Anesthesiology and Pain Medicine and Anesthesia, Seoul

All Listed Sponsors
lead

Yonsei University

OTHER

NCT02480088 - Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism | Biotech Hunter | Biotech Hunter