Evaluation of Safety and Efficacy of DCVAC/LuCa (Immunotherapy of Lung Cancer) in Patients With Metastatic Lung Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

December 31, 2014

Primary Completion Date

January 31, 2018

Study Completion Date

November 30, 2021

Conditions
Stage IV Non-small Cell Lung Cancer
Interventions
BIOLOGICAL

DCVAC add on to SOC

DCVAC add on to SOC (Carboplatin, Paclitaxel): until progression or intolerance or death

BIOLOGICAL

DCVAC and immune enhancers add on to SOC

DCVAC +/- immune enhancers (Interferon-α and Hydroxychloroquine) add on to SOC (Carboplatin, Paclitaxel): until progression or intolerance or death

OTHER

Standard of Care Chemotherapy

SOC (Carboplatin, Paclitaxel): until progression or intolerance or death

Trial Locations (18)

625 00

Brno

500 05

Hradec Králové

377 38

Jindřichův Hradec

284 01

Kutná Hora

547 69

Náchod

775 20

Olomouc

708 52

Ostrava

530 03

Pardubice

305 99

Pilsen

128 08

Prague

140 59

Prague

150 06

Prague

261 95

Příbram

401 13

Ústí nad Labem

762 75

Zlín

040 01

Košice

921 01

Piešťany

058 01

Poprad

All Listed Sponsors
lead

SOTIO a.s.

INDUSTRY

NCT02470468 - Evaluation of Safety and Efficacy of DCVAC/LuCa (Immunotherapy of Lung Cancer) in Patients With Metastatic Lung Cancer | Biotech Hunter | Biotech Hunter