Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric

PHASE4CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

April 30, 2014

Primary Completion Date

June 30, 2014

Study Completion Date

July 31, 2014

Conditions
Specified SedativeHypnotic
Interventions
DRUG

Diphenhydramine

Intravenous Injection

DRUG

normal saline

Intravenous Injection

DRUG

Ketamine

Ketamine 0,1 mg/kg intravenously used as rescue tranquilizer if the subject becomes agitated, repeated dose of 0,05 mg/kg every minute can be given if the agitation does not resolve, maximum ketamine dose for tranquilizer 0,25 mg/kg to prevent deep sedation

DRUG

Sevoflurane

Sevoflurane as single sedation agent for general anesthesia in both arm. 8% Sevoflurane in 100% oxygen used as induction agent, and 2% sevoflurane in 50% oxygen used as maintenance agent

DRUG

Bupivacaine

Bilateral extraoral infraorbital nerve block with 0,125% Bupivacaine as analgetic for operation and post operation.

All Listed Sponsors
collaborator

Permata Sari Hospital for Plastic Surgery

UNKNOWN

lead

Universitas Diponegoro

OTHER

NCT02463929 - Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric | Biotech Hunter | Biotech Hunter