Improving Insulin Resistance To Treat Non-Alcoholic Fatty Liver Disease: A Pilot Study

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

June 30, 2015

Primary Completion Date

July 31, 2017

Study Completion Date

July 31, 2017

Conditions
Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions
DRUG

Metformin

Although metformin is FDA approved to treat type 2 diabetes, it is not FDA approved for the treatment of NAFLD and is considered investigational for the purpose of this study.

BEHAVIORAL

Lifestyle modifications

Recommendations for lifestyle modification will be based on the Diabetes Prevention Program 2002 (26) and will include recommendations for greater than 150 minutes of physical activity weekly, referrals to group and/or individualized sessions with nutritionists and/or lifestyle coaches as well as educational materials

DEVICE

Fibroscan device (Echosens)

This study will be incorporating the use of a Fibroscan device (Echosens) at the initial visit and upon completion of the study, which works by measuring shear wave velocity.

Trial Locations (1)

11030

North Shore Hospital, Manhasset

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Northwell Health

OTHER