Evaluation of the Safety, Efficacy, and Pharmacokinetics of Intravenous Deferiprone in HIV-Positive Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

March 31, 2016

Study Completion Date

May 31, 2016

Conditions
Asymptomatic HIV Infection
Interventions
DRUG

Intravenous deferiprone

In Cohort 1, the subjects who were randomized to get active product will receive deferiprone at a dose of 1.5 g per infusion, and if there are no significant safety concerns, the subjects in Cohort 2 who were randomized to get active product will receive it a a dose of 2 g per infusion.

DRUG

Placebo

In both cohorts, the subjects who were randomized to get placebo will receive an infusion of placebo solution that is equal in volume to that of the active product.

Trial Locations (2)

6001

Phoenix Pharma, Port Elizabeth

0087

VxPharma, Pretoria

Sponsors

Lead Sponsor

All Listed Sponsors
lead

ApoPharma

INDUSTRY

NCT02456558 - Evaluation of the Safety, Efficacy, and Pharmacokinetics of Intravenous Deferiprone in HIV-Positive Subjects | Biotech Hunter | Biotech Hunter