Renal Perfusion, Filtration and Oxygenation After Liver Transplantation -Effects of av Postoperative Blood Pressure

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

February 29, 2016

Study Completion Date

February 29, 2016

Conditions
Acute Kidney InjuryLiver Failure
Interventions
OTHER

Alternating mean arterial pressure

In normovolemic patients directly after liver transplantation, target mean arterial pressure is altered using norepinephrine according to study protocol.

DRUG

Norepinephrine

Infusion rate of norepinephrine is raised and lowered, respectively, in order to reach MAP 60, 75 and 90 mmHg in patients already requiring vasopressor for adequate blood pressure control.

DRUG

Chromium ethylenediaminetetraacetic acid

Extraction of 51Cr-EDTA measured for FF and GFR

Trial Locations (1)

41345

Sahlgrenska University Hospital, dpt of anesthesiology and intensive care, Gothenburg

All Listed Sponsors
lead

Sahlgrenska University Hospital

OTHER

NCT02455115 - Renal Perfusion, Filtration and Oxygenation After Liver Transplantation -Effects of av Postoperative Blood Pressure | Biotech Hunter | Biotech Hunter