Evaluate Safety and Efficacy of ORADUR®-Methylphenidate in Children and Adolescents With ADHD

PHASE3CompletedINTERVENTIONAL
Enrollment

114

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

February 28, 2017

Study Completion Date

February 28, 2017

Conditions
Attention Deficit Hyperactivity Disorder
Interventions
DRUG

Placebo First, then ORADUR®

ORADUR®-Methylphenidate is available in three dosage forms (22mg, 33mg or 44mg). The optimal dose for each subject will be determined in the open-label titration period. After randomization, subjects will be subjected to the 4-week double-blind two-way cross-over treatment phase with 2 study periods (2 weeks of placebo and 2 weeks of ORADUR®-Methylphenidate oral capsule at the optimal dose, according to a pre-determined randomization schedule).

DRUG

ORADUR® First, then Placebo

ORADUR®-Methylphenidate is available in three dosage forms (22mg, 33mg or 44mg). The optimal dose for each subject will be determined in the open-label titration period. After randomization, subjects will be subjected to the 4-week double-blind two-way cross-over treatment phase with 2 study periods (2 weeks of placebo and 2 weeks of ORADUR®-Methylphenidate oral capsule at the optimal dose, according to a pre-determined randomization schedule).

Trial Locations (4)

100

National Taiwan University Hospital, Taipei

114

Tri-Service General Hospital, Taipei

Unknown

Chang Gung Medical Foundation- Chiayi Branch, Chiayi City

Chang Gung Medical Foundation- Linkuo Branch, Taoyuan District

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Durect

INDUSTRY

lead

Orient Pharma Co., Ltd.

INDUSTRY