30
Participants
Start Date
March 31, 2014
Primary Completion Date
September 30, 2016
Study Completion Date
December 31, 2016
BM-MSCs/fibrin glue/collagen fleece
Xeno-free, clinical-grade, autologous alveolar bone marrow mesenchymal stem cells enriched with autologous fibrin glue and loaded into a commercially available collagen fleece.
Fibrin glue/collagen fleece
The biocomplex of autologous fibrin glue and collagen fleece devoid of stem cells will fill the osseous defect
Open flap debridement
Group C will receive minimally invasive surgery employing papilla preservation techniques in addition to retaining the soft tissue wall of the pocket. There will be no use of grafting materials
Dental School, Aristotle University, Thessaloniki
University of Glasgow
OTHER
Aristotle University Of Thessaloniki
OTHER