500
Participants
Start Date
June 11, 2015
Primary Completion Date
February 20, 2026
Study Completion Date
February 20, 2026
Instructions
In sub-study 1, half the participants are instructed about outcomes, half learn through experience.
Attention
In sub-study 4, participants learn about outcomes and we manipulate attention toward or away from the pain.
Thermal Pain
In sub-studies 2 and 3, participants are exposed to thermal stimuli and/or tastants (sugar water, salt water, neutral rinse) and we are measuring how learning varies based on the type of outcome.
Placebo instructions
In sub-study 5, we test whether placebo effects and expectancy cues modulate pain through similar mechanisms.
RECRUITING
National Institutes of Health Clinical Center, Bethesda
National Center for Complementary and Integrative Health (NCCIH)
NIH