rTMS Therapy for Primary Orthostatic Tremor

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

January 8, 2019

Study Completion Date

January 8, 2019

Conditions
Primary Orthostatic Tremor
Interventions
DEVICE

Magstim RapidStim2

Application of repetitious transcranial magnetic stimulation (TMS) pulses using Magstim RapidStim2 to a specific brain target at predefined stimulation parameters.

DEVICE

Sham Magstim RapidStim2

Same procedure as real rTMS without stimulating the cerebral cortex.

OTHER

Fullerton Advanced Balance (FAB) Scale

All participants will receive a clinical assessment of balance ability and fall risk.

OTHER

"Timed Up & Go Test (TUG) test"

All participants will receive a clinical assessment of basic mobility skills by using the TUG test.

OTHER

10m walk test

All participants will receive a clinical assessment of walking speed by using the walk test.

OTHER

Tremor electrophysiology

All participant tremors will by analyzed using an EMG system

OTHER

Cerebellar-brain Inhibition (CBI)

All participants will have a measure of the cerebellar-brain inhibition (CBI) which will be conducted by using a TMS device determining the ability of the coil to activate the cerebellum.

Trial Locations (1)

32607

Center for Movement Disorders and Neurorestoration, Gainesville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Organization for Rare Disorders

OTHER

collaborator

Neuronetics

OTHER

lead

University of Florida

OTHER

NCT02441985 - rTMS Therapy for Primary Orthostatic Tremor | Biotech Hunter | Biotech Hunter