Neurocircuit Mechanisms of OCD Across the Lifespan

NACompletedINTERVENTIONAL
Enrollment

206

Participants

Timeline

Start Date

March 9, 2015

Primary Completion Date

April 13, 2020

Study Completion Date

October 21, 2020

Conditions
Obsessive-Compulsive Disorder
Interventions
BEHAVIORAL

Cognitive Behavioral Therapy - Adolescents

"A therapy which gradually yet repeatedly exposes adolescent patients to their obsessive compulsive-relevant error cues during a task performance until their anxiety habituates."

BEHAVIORAL

Stress Management Therapy - Adolescents

An active control therapy with minimal effects on OCD symptoms.

BEHAVIORAL

Optional CBT - Adolescents

This is the cross-over element for those that completed the SMT treatment group and opt to have the OCD treatment.

BEHAVIORAL

Cognitive Behavioral Therapy - Adults

"A therapy which gradually yet repeatedly exposes adult patients to their obsessive compulsive-relevant error cues during a task performance until their anxiety habituates."

BEHAVIORAL

Stress Management Therapy - Adults

An active control therapy with minimal effects on OCD symptoms.

BEHAVIORAL

Optional CBT - Adults

This is the cross-over element for those that completed the SMT treatment group and opt to have the OCD treatment.

OTHER

fMRI only - Healthy Control Adults

Two fMRI's only, scheduled at 12-weeks apart. This is for Healthy Control Adults and is used only as a means for observation, NOT as an intervention to be studied.

OTHER

fMRI only - Healthy Control Adolescents

Two fMRI's only, scheduled at 12-weeks apart. This is for Healthy Control Adolescents and is used only as a means for observation, NOT as an intervention to be studied.

Trial Locations (1)

48109

University of Michigan, Ann Arbor

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Michigan

OTHER

NCT02437773 - Neurocircuit Mechanisms of OCD Across the Lifespan | Biotech Hunter | Biotech Hunter