Experimental Falciparum Transmission to Anopheles

PHASE1CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

April 30, 2015

Primary Completion Date

September 30, 2016

Study Completion Date

September 30, 2016

Conditions
Malaria
Interventions
BIOLOGICAL

Administration of the malaria inoculum

Each participant in the cohort will be inoculated on Day 0 with \~2,800 viable parasites of Plasmodium falciparum-infected human erythrocytes (BSPC) administered intravenously. The threshold for commencement of treatment will be when PCR quantification of all participants is ≥ 5,000 parasites/mL.

DRUG

Piperaquine Phosphate 480 mg

When PCR quantification of all participants is ≥ 5,000 parasites/mL, participants will receive a single dose of 480 mg Piperaquine Phosphate

Trial Locations (1)

4006

Q-Pharm Clinics, Herston

All Listed Sponsors
collaborator

Q-Pharm Pty Limited

INDUSTRY

collaborator

Clinical Network Services (CNS) Pty Ltd

INDUSTRY

collaborator

Sullivan Nicolaides Pathology

INDUSTRY

collaborator

QIMR Berghofer Medical Research Institute

OTHER

collaborator

Army Malaria Institute, Australia

OTHER

lead

Medicines for Malaria Venture

OTHER

NCT02431637 - Experimental Falciparum Transmission to Anopheles | Biotech Hunter | Biotech Hunter