A Study Assessing Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

147

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

February 28, 2017

Study Completion Date

February 28, 2017

Conditions
Alzheimer's Disease
Interventions
DRUG

Bryostatin 1

The investigational drug product, bryostatin, is a sterile, pyrogen-free, lyophilized powder intended for IV infusion upon reconstitution and dilution. Placebo is a sterile, pyrogen-free, lyophilized powder intended for IV infusion upon reconstitution and dilution.

OTHER

Placebo

The placebo is a sterile, pyrogen-free, lyophilized powder identical in appearance to the active drug, intended for IV infusion upon reconstitution and dilution.

Trial Locations (29)

11040

Parker Jewish Institute for Health Care and Rehabilitation, New Hyde Park

12208

Neurological Associates of Albany, PC, Albany

28270

Alzheimer's Memory Center, Charlotte

30030

iResearch Atlanta, Decatur

30331

Atlanta Center for Medical Research, Atlanta

32162

Compass Research, The Villages

32763

Medical Research Group of Central Florida, Orange City

32806

Compass Research, LLC, Orlando

33137

Miami Jewish Health System, Miami

33445

Brain Matters Research, Delray Beach

33449

Alzheimer's Research and Treatment Center, Lake Worth

33462

JEM Research, Atlantis

33609

Axiom Clinical Research of Florida, Tampa

33912

Neuropsychiatric Research Center of South Florida, Fort Myers

38018

Neurology Clinic, PC, Cordova

44718

Neurobehavioral Clinical Research, Canton

60007

Alexian Brothers Neurosciences Institute Clinical Research, Elk Grove Village

63141

Millennium Psychiatric Associates, Creve Coeur

66205

University of Kansas Alzheimer's Disease Center, Fairway

70629

Lake Charles Clinical Trials, Lake Charles

71104

J. Gary Booker, MD APMC Clinical Drug Trials, Shreveport

73112

Oklahoma Clinical Research Center, Oklahoma City

85004

Xenoscience, Inc/ 21st Century Neurology, Phoenix

90720

Nader Pharmacology Research Institute, Los Alamitos

92626

ATP Clinical Research, Inc., Costa Mesa

94109

San Francisco Clinical Research Center, San Francisco

97504

Sunstone Clinical Research, Medford

07801

Atlantic Neuroscience Institute, Springfield

Unknown

The Clinical Trial Center, LLC, Jenkintown

Sponsors
All Listed Sponsors
lead

Neurotrope Bioscience, Inc.

INDUSTRY