Mocetinostat (MGCD0103) Plus Brentuximab Vedotin (SGN-35) in Patients With Relapsed or Refractory Hodgkin Lymphoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

April 22, 2015

Primary Completion Date

February 17, 2021

Study Completion Date

February 17, 2021

Conditions
Hodgkin Lymphoma
Interventions
DRUG

Mocetinostat Plus Brentuximab Vedotin

All patients will receive a 1-week lead-in with mocetinostat alone (administered days 1, 3, and 5). Patients with palpable peripheral lymph nodes will undergo FNA before and after this 1 week treatment. Cycle 1 will then begin 15 days (+/-3 days) following initiation of the lead-in.

Trial Locations (1)

10065

Memorial Sloan Kettering Cancer Center, New York

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

MethylGene Inc.

INDUSTRY

lead

Memorial Sloan Kettering Cancer Center

OTHER