A Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis.

PHASE4CompletedINTERVENTIONAL
Enrollment

221

Participants

Timeline

Start Date

April 20, 2015

Primary Completion Date

February 12, 2016

Study Completion Date

November 22, 2016

Conditions
Parapsoriasis
Interventions
DRUG

Apremilast

Apremilast 30 mg tablets orally twice daily (BID) weeks 0 to 52.

DRUG

Placebo

Participants randomized to the placebo treatment group received placebo tablets (identical in appearance to the apremilast 30 mg tablets) orally BID for from weeks 0-16.

DRUG

Placebo-Apremilast

At Week 16, those randomized to placebo were switched to apremilast 30mg BID for an additional 36 weeks (52 weeks total)

Trial Locations (26)

10075

Sadick Research Group, New York

11530

Garden City Dermatology, Garden City

14623

Dermatology Associates of Rochester PC, Rochester

20850

Lawrence Green, MD, LLC, Rockville

24501

Dermatology Consultants, Inc., Lynchburg

29414

Dermatology and Laser Center of Charleston, Charleston

31217

Dermatologic Surgery Specialists, P.C., Macon

33612

USF Health Faculty Office Building-FOB, Tampa

33624

Forward Clinical Trials Inc, Tampa

35233

UAB at Birmingham - The Kirklin Clinic, Birmingham

40202

Dermatology Specialists, PSC, Louisville

40217

DermResearch, PLLC, Louisville

46032

Shideler Clinical Research Center, Carmel

48202

Henry Ford Hospital, Detroit

84132

University of Utah School of Medicine, Salt Lake City

89052

Las Vegas Skin and Cancer Clinics, Las Vegas

90045

Dermatology Research Associates, Los Angeles

92663

Blue Harbor Dermatology, Newport Beach

92780

Tien Q. Nguyen MD Inc, Tustin

94538

Center For Dermatology, Fremont

94578

East Bay Rheumatology Medical, San Leandro

95819

Center for Dermatology and Laser Surgery, Sacramento

06030

UConn Health Center, Farmington

32405-4542

Dermatology Associates, Panama City

08520

Psoriasis Treatment Center of Central New Jersey, East Windsor

45267-0501

University of Cincinnati, Cincinnati

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY