26
Participants
Start Date
March 31, 2015
Primary Completion Date
August 31, 2020
Study Completion Date
August 31, 2020
Hiltonol
"Wk 1 Days 1, 3 and 5: Poly-ICLC (Hiltonol®) 1 mg (0. 5 ml) IntraTumoral (priming treatment course). Weeks 2-25 Poly-ICLC (Hiltonol®) 1 mg (0.5 ml) IM twice a week with a 48-72 hour interval between the two injections, AND either:~No additional immunotherapy OR~ONLY ONE of the Anti-PD1 or anti-PDL-1 regimens will be administered, per manufacturer's dosing and clinical oncologist's discretion as follows: (Not to be Administered on the same day as Poly-ICLC \[Hiltonol®\]) Either Nivolumab, OR Pembrolizumab, OR Atezolizumab, OR Cemiplimab, OR Durvalumab"
Icahn School of Medicine at Mount Sinai, New York
Chevy Chase RCCA, Chevy Chase
Dermatologic Surgery Center Washington DC, Chevy Chase
Bay Hematology Oncology, Easton
University of Missouri School of Medicine, Columbia
Lead Sponsor
National Institutes of Health (NIH)
NIH
Icahn School of Medicine at Mount Sinai
OTHER
Bay Hematology Oncology
UNKNOWN
National Cancer Institute (NCI)
NIH
University of Missouri-Columbia
OTHER
Chevy Chase Regional Cancer Care Associates LLC
UNKNOWN
Dermatologic Surgery Center of Washington LLC and Skin Cancer Treatment Center
UNKNOWN
Oncovir, Inc.
INDUSTRY