NCT02423603 - PAKT: AZD5363 in Combination With Paclitaxel in Triple-Negative Advanced or Metastatic Breast Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 14, 2014

Primary Completion Date

June 30, 2017

Study Completion Date

June 30, 2024

Conditions

Metastatic Breast Cancer

Interventions

DRUG

Paclitaxel

Patient receive Once a week for three weeks - with one week off treatment

DRUG

AZD5363

Patients receive AZD5363/Placebo in an intermittent treatment schedule. Please see study arms for full information.

DRUG

Placebo

Patients receive AZD5363/Placebo in an intermittent treatment schedule. Please see study arms for full information.

Trial Locations (46)

Unknown

ICO René Gauducheau, Nantes

Centre André-lacassagne, Nice

Centre Hospitalier Prive Saint-Gregoire, Saint-Grégoire

Institute of Clinical Oncology, Tbilisi

Országos Onkológiai Intézet, Budapest

University of Pécs - Clinical Center Institute of Oncotherapy, Pécs

Zala County Hospital Szent Rafael, Zalaegerszeg

Prof. Dr. I. Chiricuta Oncology Institute, Cluj-Napoca

Sf. Nectarie SRL Oncologie Medical Center, Craiova

Center of Oncology Euroclinic, Iași

Chungbuk National University Hospital, Cheongju-si

National Cancer Center, Goyang-si

Asan Medical Center, Seoul

Korea University Guro Hospital, Seoul

Samsung Medical Centre, Seoul

Yonsei University Health System, Seoul

LL57 2PW

Betsi Cadwaladr University Health Board, Bangor

BT9 7AB

Belfast Health and Social Care Trust, Belfast

LL18 5UJ

Glan Clwyd Hospital BCU Health Board NHS Wales, Bodelwyddan

Ysbyty Wrexham Maelor Hospital, Wrexham

BN2 5BE

Brighton and Sussex University Hospitals NHS Trust, Brighton

CB2 0QQ

Cambridge University Hospitals NHS Foundation Trust, Cambridge

CT1 3NG

East Kent Hospitals University NHS Foundation Trust, Canterbury

CF14 2TL

Velindre Cancer Centre, Cardiff

CV2 2DX

University Hospitals Coventry and Warwickshire NHs Trust, Coventry

EH4 2XR

NHS Lothian, Edinburgh

ME7 5NY

Medway NHS Foundation Trust, Gillingham

G12 0YN

Beatson West of Scotland Cancer Centre, Glasgow

LS9 7TF

Leeds Teaching Hospitals NHs Trust, Leeds

EC1M 6BQ

Barts Health NHS Trust, London

NW1 2PG

University College London Hospitals, London

RM7 0AG

Barking, Havering and Redbridge University Hospitals NHS Trust, London

SE1 9RT

Guys and St Thomas' NHS Foundation Trust, London

SE18 4QH

Lewisham and Greenwich NHS Trust, London

SW3 6JJ

Royal Marsden NHS Foundation Trust-Fulham, London

W2 1NY

Imperial College Healthcare NHS Trust, London

ME16 9QQ

Maidstone and Tunbridge Wells NHS Trust, Maidstone

M20 4BX

The Christie NHS Foundation Trust, Manchester

NG5 1PB

Nottingham University Hospitals NHS Trust, Nottingham

SO16 6YD

Southampton University Hospitals NHS Trust, Southampton

SS0 0RY

Southend University Hospital NHS Foundation Trust, Southend

ST4 6QG

University Hospital of North Staffordshire NHS Trust, Stoke-on-Trent

SM2 5PT

Royal Marsden - Sutton, Sutton

SA2 8QA

Abertawe Bro Margannwg University Health Board, Swansea

TR1 3LJ

Royal Cornwall Hospitals NHS Trust, Truro

BA21 4AT

Yeovil District Hospital NHS Foundation Trust, Yeovil