55
Participants
Start Date
April 30, 2015
Primary Completion Date
December 31, 2021
Study Completion Date
August 27, 2022
Paclitaxel
"* Administered intravenously (IV)~* Prescribed at 200 mg/m2 (standard dose)~* Given once every 21 days (i.e., one cycle)~* Up to 4 cycles are administered depending on disease response"
Carboplatin
"* Administered intravenously (IV)~* Prescribed at AUC = 6 using the Cockcroft-Gault formula (standard dose)~* Given once every 21 days (i.e., one cycle)~* Up to 4 cycles are administered depending on disease response"
Ascorbic Acid
"* Administered intravenously (IV)~* 75g per infusion~* Two infusions per week~* 1 cycle is 3 weeks~* given up to 4 cycles~* may be given while chemotherapy if delayed due to low counts"
Holden Comprehensive Cancer Center, Iowa City
Collaborators (1)
National Cancer Institute (NCI)
NIH
National Institutes of Health (NIH)
NIH
Holden Comprehensive Cancer Center
OTHER
McGuff Pharmaceuticals, Inc.
INDUSTRY
Joseph J. Cullen, MD, FACS
OTHER