Vulvar Lichen Sclerosus: Comparison Between Clobetasol Propionate, Photodynamic Therapy and Low-Intensity Laser

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

August 31, 2016

Study Completion Date

October 31, 2017

Conditions
Vulvar Lichen Sclerosus
Interventions
DRUG

Clobetasol propionate

Clobetasol propionate 0.05% ointment applied once daily at a dose of 1 g/application (1 g sachets) for 4 weeks.

RADIATION

Photodynamic therapy

Methylene blue 0.01% intralesional, λ = 660 ± 10 nm, P = 100 mW, PD = 510 mW/cm2, E = 4 J, ED = 20 J/cm2, t = 40 s, once a week for 4 weeks

RADIATION

Low level laser therapy

λ = 660 ± 10 nm, P = 100 mW, PD = 510 mW/cm2, E = 4 J, ED = 20 J/cm2, t = 40 s, once a week for 4 weeks

Trial Locations (1)

01314000

Hospital Pérola Byington, São Paulo

All Listed Sponsors
collaborator

Hospital Perola Byington

OTHER_GOV

lead

Daniela de Fátima Teixeira da Silva

OTHER

NCT02416531 - Vulvar Lichen Sclerosus: Comparison Between Clobetasol Propionate, Photodynamic Therapy and Low-Intensity Laser | Biotech Hunter | Biotech Hunter