NCT02406261 - A Drug-Drug Interaction Study of Lanabecestat (LY3314814) in Healthy Participants | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 30, 2015

Primary Completion Date

August 31, 2015

Study Completion Date

August 31, 2015

Conditions

Healthy

Interventions

DRUG

Lanabecestat

50 mg lanabecestat will be administered orally as 1 × 50-mg tablet

DRUG

Simvastatin

20 mg simvastatin will be administered orally as 1 × 20-mg tablet

DRUG

Midazolam

500 mcg midazolam will be administered orally as 0.25 mL of 2-mg/mL syrup

DRUG

Midazolam

250 mcg midazolam will be administered intravenous (IV) as 0.25 mL of 1-mg/mL injection solution

DRUG

Donepezil

5 mg donepezil will be administered orally as 1 × 5-mg tablet

DRUG

Lanabecestat

50 mg lanabecestat will be administered orally as 1 × 50-mg tablet

Trial Locations (2)

Covance Inc, Daytona Beach

Covance Inc, Dallas