NCT02406066 - Single and Multiple Rising Dose Study of Safety and PK of Metyrapone/Oxazepam Combination (EMB-001) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 31, 2015

Primary Completion Date

December 31, 2015

Study Completion Date

June 30, 2016

Conditions

Cocaine Use DisorderTobacco Use Disorder

Interventions

DRUG

metyrapone & oxazepam

6 subjects will receive active study drug (a low dose combination of metyrapone \& oxazepam) and 2 subjects will receive placebo.

DRUG

metyrapone & oxazepam

6 subjects will receive active study drug (a medium dose combination of metyrapone \& oxazepam) and 2 subjects will receive placebo.

DRUG

metyrapone & oxazepam

6 subjects will receive active study drug (a high dose combination of metyrapone \& oxazepam) and 2 subjects will receive placebo.

DRUG

Placebo

Each cohort will have 2 subjects receiving placebo

Trial Locations (2)

Pennington Biomedical Research Center, Baton Rouge

Collaborative Neuroscience Network, LLC, Long Beach