139
Participants
Start Date
March 31, 2015
Primary Completion Date
November 23, 2020
Study Completion Date
February 15, 2021
Targeted Cognitive Training
Targeted Cognitive Training is performed on the computer through Posit Science. Games are modern and engaging modifications of classic neuropsychological tests, such as set-shifting games modeled on the Wisconsin Card Sort Test, and cognitive control games modeled on Stroop-like interference tasks. Games will target two sets of skills: Targeted cognitive skills include: processing speed, memory, attention, flexibility/cognitive-control, and problem-solving. After 20 hours of training on these skills, participants will complete 20 hours of training on core social cognitive skills, including facial affect recognition, gaze direction perception, and face identity recognition, and theory of mind.
Computer Games
The comparison intervention consists of 40 hours of commercially available and cognitively non-specific computer games. These computer games - such as checkers, solitaire, crossword puzzles - are entertaining and engaging but do not target specific neurocognitive skills.
Rush University Medical Center, Chicago
Harvard Medical School (HMS and HSDM)
OTHER
Beth Israel Deaconess Medical Center
OTHER
National Institute of Mental Health (NIMH)
NIH
Rush University Medical Center
OTHER