Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

459

Participants

Timeline

Start Date

April 30, 2015

Primary Completion Date

August 31, 2016

Study Completion Date

November 30, 2016

Conditions
Complex Regional Pain Syndrome, Type I
Interventions
DRUG

Placebo

Matching placebo administered as intravenous infusion.

DRUG

Neridronic acid 62.5 mg

Neridronic acid administered as intravenous infusion.

Trial Locations (59)

10467

Site US137 - Montefiore Medical Center, The Bronx

12208

Site US166 - Albany Medical College, Albany

14618

Site US145 - University of Rochester, Rochester

19090

Site US114 - Abington Neurological Associates, Willow Grove

19152

Site US149 - Founders Research Corporation, Philadelphia

27103

Site US135 - The Center for Clinical Research, Winston-Salem

29406

Site US112 - Clinical Trials of South Carolina, Charleston

30159

Site DE101 - Klinische Forschung Hannover Mitte GmbH, Hanover

30265

Site US131 - Better Health Clinical Research, Inc, Newnan

32806

Site US104 - Discovery Clinical Trials, Orlando

32953

Site US143 - Florida Pain Institute, Merritt Island

33016

Site US122 - Precision Research Organization, LLC, Miami Lakes

33130

Site US111 - Sunrise Research Institute, Miami

33317

Site US133 - Gold Coast Research LLC, Plantation

33409

Site US165 - Palm Beach Research, West Palm Beach

33603

Site US121 - Clinical Research of West Florida, Tampa

33709

Site US171 - Florida Medical Pain Management, St. Petersburg

33765

Site US153 - Clinical Research of West Florida Inc - Clearwater, Clearwater

34711

Site US162 - South Lake Pain Institute, Clermont

36535

Site US119 - G & L Research, Foley

44130

Site US157 - North Star Medical Research, Middleburg Heights

60640

Site US103 - Great Lakes Clinical Trials, Chicago

63128

Site US127 - Advance Clinical Research, Inc, St Louis

66210

Site US129 - International Clinical Research Institute, Overland Park

70736

Site DE104 - Schmerzzentrum Dr. med. C. Wachter & T. Tusker, Fellbach

72211

Site US154 - Woodland International Research Group, Little Rock

77099

Site US113 - Pioneer Research Solutions, Inc, Houston

78756

Site US107 - Austin Center for Clinical Research, Austin

78758

Site US134 - Lovelace Scientific Resources, Inc, Austin

80209

Site US106 - Mountain View Clinical Research, Denver

80799

Site DE103 - Algesiologikum Studienzentrum und Algesiologikum MVZ, Munich

84088

Site US164 - Advanced Clinical Research, West Jordan

84106

Site US118 - Omega International Pain Clinic, Salt Lake City

85254

Site US117 - Valley Pain Consultants, Scottsdale

85258

Site US116 - Arizona Pain Specialists, Scottsdale

85712

Site US124 - Quality of Life Medical and Research Centers LLC, Tucson

89123

Site US105 - Advanced Biomedical Research of America, Las Vegas

90703

Site US172 - Core Healthcare Group, Cerritos

91710

Site US108 - Catalina Research Institute, Chino

92093

Site US152 - UC San Diego Healthcare Systems, Center for Pain Medicine, La Jolla

92324

Site US175 - Inland Pain Medicine, Colton

92801

Site US110 - Orange County Research Institute, Anaheim

95032

Site US102 - Samaritan Center for Medical Research, Los Gatos

95821

Site US126 - Northern California Research, Sacramento

97080

Site DE102 - Universitätsklinikum Würzburg Neurologische Klinik, Würzburg

98004

Site US144 - Bellevue Surgery Center, Bellevue

Site US173 - Bellevue Surgery Center, Bellevue

98007

Site US123 - Northwest Clinical Research Center, Bellevue

98104

Site US161 - Swedish Pain and Headache Center, Seattle

01773

Site US169 - Massachusetts General Hospital, Boston

08540

Site US101 - Princeton Medical Institute, Princeton

07702

Site US151 - Premier Pain Centers, Shrewsbury

08502

Site US156 - University Clinical Research Center, Somerset

04564

Site DE107 - Studienzentrum A. Schwittay, Böhlen

NE1 4LP

Site GB104 - The Royal Victoria Infirmary, Cambridge

DL3 6HX

Site GB108 - Darlington Memorial Hospital, Centre for Research and clinical Intervention, Darlington

EX2 5DW

Site GB109 - Royal Devon Exeter Hospital, Exeter

SE1 7EH

Site GB101 - Guys and St. Thomas NHS Foundation Trust - St Thomas Hospital, London

SW10 9NH

Site GB111 - Chelsea and Westminster Hospital - NHS Foundation Trust, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Grünenthal GmbH

INDUSTRY