Study to Assess the Bioavailability of Ticagrelor OD Tablet vs. IR Tablet

PHASE1CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

July 31, 2015

Study Completion Date

July 31, 2015

Conditions
BioavailabilityHealthy Subjects
Interventions
DRUG

Ticagrelor OD tablet (90 mg single dose) administered with 200 ml of water

90 mg single dose

DRUG

Ticagrelor OD tablet (90 mg single dose) administered without water

90 mg single dose

DRUG

Ticagrelor OD tablet (90 mg single dose) suspended in water administered via nasogastric tube

90 mg single dose

DRUG

Brilique®, Ticagrelor IR tablet (90 mg) administered with 200mL of water

90 mg single dose

Trial Locations (1)

Unknown

Research Site, Berlin

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY