Study of ACY-241 Alone and in Combination With Pomalidomide and Dexamethasone in Multiple Myeloma

PHASE1TerminatedINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

May 7, 2015

Primary Completion Date

June 3, 2024

Study Completion Date

June 3, 2024

Conditions
Multiple Myeloma
Interventions
DRUG

ACY-241

Dose escalation up to 480 mg administered orally on Days 1-21 of a 28 day cycle.

DRUG

Pomalidomide

4 mg qd dosed on days 1-21 of a 28 day cycle

DRUG

Dexamethasone

40 mg qd on days 1, 8, 15, 22

Trial Locations (17)

10065

Local Institution - 101, New York

30322

Local Institution - 103, Atlanta

31008

Local Institution - 301, Pamplona

33612

Local Institution - 108, Tampa

37007

Local Institution - 300, Salamanca

44093

Local Institution - 341, Nantes

44718

Gabrail Cancer Center Research, Canton

59037

Local Institution - 340, Lille

69120

Local Institution - 330, Heidelberg

78229

CTRC at The UT Health Science Center at San Antonio, San Antonio

80218

Colorado Blood Cancer Institute, Denver

85719

Local Institution - 109, Tucson

98104

Local Institution - 111, Seattle

33136-2107

University of Miami Medical Center, Miami

02114

Local Institution - 104, Boston

02215

Local Institution - 105, Boston

115 28

Local Institution - 320, Athens

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY