1,865
Participants
Start Date
October 31, 2014
Primary Completion Date
May 31, 2017
Study Completion Date
May 31, 2017
Rapid diagnosis of AKI cause
"The Outreach team will advise on an evidence-based package of care:~1\) Rapidly establish a credible diagnosis of the cause of AKI including:~1. Improved assessment of volume status~2. Standardised use of urine dipstick .~3. Appropriate sepsis investigations.~4. Urgent ultrasound with suspected obstruction."
Rapid treatment of AKI cause
Rapid, limited treatment of hypovolaemia, with avoidance of iatrogenic fluid overload, recently recognised as a significant cause of mortality in AKI. Rapid sepsis therapy. Urgent relief of urinary tract obstruction.
Stopping 'nephrotoxic' drugs
Cessation of all potentially nephrotoxic drugs.
Early nephrology followup for stage 3 AKI
A rapid followup at discharge in an AKI clinic for survivors of stage 3 AKI, within 7 days of discharge for those in hospital, or within 7 days of the Alert for those not admitted to hospital.
Preventing recurrent AKI
Patients with AKI in the Intervention arm will receive information on preventing AKI during the study.
Good standard care
Good standard care will be provided for all patients in non Experimental arms; clinicians will continue to be able to rapidly refer patients for Nephrology advice or review; online guidance will be available for all clinicians and noted in the alerts for all cases of AKI.
Heart of England hospital NHS trust, Birmingham
University of Birmingham
OTHER
University of Warwick
OTHER
Heart of England NHS Trust
OTHER