Acute Kidney Outreach to Reduce Deterioration and Death (AKORDD)

NACompletedINTERVENTIONAL
Enrollment

1,865

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

May 31, 2017

Study Completion Date

May 31, 2017

Conditions
Acute Kidney Injury
Interventions
OTHER

Rapid diagnosis of AKI cause

"The Outreach team will advise on an evidence-based package of care:~1\) Rapidly establish a credible diagnosis of the cause of AKI including:~1. Improved assessment of volume status~2. Standardised use of urine dipstick .~3. Appropriate sepsis investigations.~4. Urgent ultrasound with suspected obstruction."

OTHER

Rapid treatment of AKI cause

Rapid, limited treatment of hypovolaemia, with avoidance of iatrogenic fluid overload, recently recognised as a significant cause of mortality in AKI. Rapid sepsis therapy. Urgent relief of urinary tract obstruction.

OTHER

Stopping 'nephrotoxic' drugs

Cessation of all potentially nephrotoxic drugs.

OTHER

Early nephrology followup for stage 3 AKI

A rapid followup at discharge in an AKI clinic for survivors of stage 3 AKI, within 7 days of discharge for those in hospital, or within 7 days of the Alert for those not admitted to hospital.

OTHER

Preventing recurrent AKI

Patients with AKI in the Intervention arm will receive information on preventing AKI during the study.

OTHER

Good standard care

Good standard care will be provided for all patients in non Experimental arms; clinicians will continue to be able to rapidly refer patients for Nephrology advice or review; online guidance will be available for all clinicians and noted in the alerts for all cases of AKI.

Trial Locations (1)

B9 5SS

Heart of England hospital NHS trust, Birmingham

All Listed Sponsors
collaborator

University of Birmingham

OTHER

collaborator

University of Warwick

OTHER

lead

Heart of England NHS Trust

OTHER

NCT02398682 - Acute Kidney Outreach to Reduce Deterioration and Death (AKORDD) | Biotech Hunter | Biotech Hunter