FLT PET/CT in Measuring Response in Patients With Previously Untreated Acute Myeloid Leukemia

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

87

Participants

Timeline

Start Date

April 20, 2016

Primary Completion Date

December 31, 2023

Study Completion Date

February 13, 2026

Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Bone Marrow Aspiration

Undergo bone marrow biopsy and aspiration

PROCEDURE

Bone Marrow Biopsy

Undergo bone marrow biopsy and aspiration

DRUG

Chemotherapy

Given anthracycline IV

PROCEDURE

Computed Tomography

Undergo FLT PET/CT

DRUG

Cytarabine

Given IV

OTHER

Fluorothymidine F-18

Undergo FLT PET/CT

OTHER

Laboratory Biomarker Analysis

Correlative studies

PROCEDURE

Positron Emission Tomography

Undergo FLT PET/CT

Trial Locations (11)

10029

Mount Sinai Hospital, New York

19104

University of Pennsylvania/Abramson Cancer Center, Philadelphia

19111

Fox Chase Cancer Center, Philadelphia

27599

UNC Lineberger Comprehensive Cancer Center, Chapel Hill

37232

Vanderbilt University/Ingram Cancer Center, Nashville

53792

University of Wisconsin Carbone Cancer Center - University Hospital, Madison

55905

Mayo Clinic in Rochester, Rochester

63110

Washington University School of Medicine, St Louis

73104

University of Oklahoma Health Sciences Center, Oklahoma City

75390

UT Southwestern/Simmons Cancer Center-Dallas, Dallas

84112

Huntsman Cancer Institute/University of Utah, Salt Lake City

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH