D-vitamin And Graves' Disease; Morbidity And Relapse Reduction

NACompletedINTERVENTIONAL
Enrollment

278

Participants

Timeline

Start Date

March 24, 2015

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions
Graves' Disease
Interventions
DIETARY_SUPPLEMENT

Cholecalciferol

One tablet per day. The duration of the intervention period is between 24-36 months. This is defined by the time of ATD treatment withdrawal, which is scheduled between approximately 12-18(-24) months after randomisation. Vitamin D supplementation will continue 12 months after withdrawal of ATD treatment or until relapse of Graves' Disease if this occurs prior.

DIETARY_SUPPLEMENT

Placebo

One tablet per day. Placebo tablet identical in appearance to cholecalciferol tablet. Duration and cessation of treatment identical to intervention with cholecalciferol.

Trial Locations (8)

2900

Gentofte Hospital, Gentofte Municipality

7400

Department of Internal Medicine, Regionshospitalet Herning, Herning

7500

Department of Internal Medicine, Regionshospitalet Holstebro, Holstebro

8000

Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus C

8600

Department of Internal Medicine, Diagnostisk Center, Regionshospitalet Silkeborg, Silkeborg

8700

Department of Internal Medicine, Regionshospitalet Horsens, Horsens

8800

Department of Internal Medicine, Regionshospitalet Viborg, Viborg

8930

Department of Internal Medicine, Regionhospitalet Randers, Randers

All Listed Sponsors
collaborator

Aarhus University Hospital

OTHER

collaborator

Regionshospitalet Silkeborg

OTHER

collaborator

Regional Hospital Holstebro

OTHER

collaborator

Regionshospitalet Horsens

OTHER

collaborator

Randers Regional Hospital

OTHER

collaborator

Regionshospitalet Viborg, Skive

OTHER

collaborator

Herning Hospital

OTHER

lead

University of Aarhus

OTHER

NCT02384668 - D-vitamin And Graves' Disease; Morbidity And Relapse Reduction | Biotech Hunter | Biotech Hunter