A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])

PHASE4CompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

March 31, 2015

Primary Completion Date

February 1, 2017

Study Completion Date

June 1, 2019

Conditions
NephrolithiasisUrinary Tract Infections
Interventions
DRUG

nitrofurantoin monohydrate/macrocrystalline capsules

1 week course of preoperative nitrofurantoin monohydrate/macrocrystalline capsules 100 milligrams twice daily

DRUG

ampicillin

IV (2 g)

DRUG

gentamicin

IV (5 mg/kg)

DRUG

vancomycin

IV (1 g)

DRUG

ceftriaxone

IV (2 g)

Trial Locations (8)

43212

The Ohio State University Wexner Medical Center, Columbus

44195

Cleveland Clinic, Cleveland

55905

Mayo Clinic, Rochester

85054

Mayo Clinic in Arizona, Phoenix

92103

UCSD Medical Center, San Diego

Unknown

UCSF, San Francisco

37232-2765

Vanderbilt, Nashville

V5Z 1M9

University of British Columbia, Vancouver

Sponsors
All Listed Sponsors
collaborator

Mayo Clinic

OTHER

collaborator

University of British Columbia

OTHER

collaborator

The Cleveland Clinic

OTHER

collaborator

Duke University

OTHER

collaborator

Ohio State University

OTHER

collaborator

Dartmouth-Hitchcock Medical Center

OTHER

collaborator

Vanderbilt University

OTHER

collaborator

New York University

OTHER

lead

University of California, San Diego

OTHER