An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders

NACompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

February 1, 2015

Primary Completion Date

January 1, 2017

Study Completion Date

January 1, 2017

Conditions
EncopresisAutistic Disorder
Interventions
DRUG

Glycerin Suppository

Nursing staff will administer one glycerin suppository in the bathroom if there is no continent bowl movement in the first 30 minutes. Subjects will be taken to the bathroom 5 minutes after the suppository is administered for a 30 minute sit or until a continent void occurs. If continent bowel movements maintain on two subsequent days (after bisacodyl suppositories are discontinued) the glycerin suppository will be discontinued. At least one primary caregiver will be trained on all components of intervention still in use on the last day their child's admission. Four weekly follow-up appointments will be used to support them as they continue to implement the protocol at home, including continuing to fade out the use of medications for participants who are at least partially continent but not fully independent at the time of discharge.

DRUG

Bisacodyl suppository

If a subject does not have a bowel movement during the 30 minute sit following administration of the glycerin suppository, they will be given a 1 hour break, after which a bisacodyl suppository will be administered. The participant will then sit for an additional 30 minutes.If continent bowel movements maintain for two subsequent days (after senna is discontinued) bisacodyl suppositories will be discontinued if it was required. At least one primary caregiver will be trained on all components of intervention still in use on the last day their child's admission. Four weekly follow-up appointments will be used to support them as they continue to implement the protocol at home, including continuing to fade out the use of medications for participants who are at least partially continent but not fully independent at the time of discharge.

DRUG

Senna

If no continent bowel movements occur for two consecutive treatment days, caregivers will be asked to administer senna each evening thereafter until medication tapering begins. Once there have been two successive days with continent bowel movements, senna will be removed from the intervention if it was required.

Trial Locations (1)

30329

Marcus Autism Center, Atlanta

All Listed Sponsors
collaborator

Organization for Autism Research

OTHER

lead

Emory University

OTHER

NCT02383758 - An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders | Biotech Hunter | Biotech Hunter